Projects and Trainings in Computational Biology Department
Module I: Introduction to Bioinformatics
Introduction to Bioinformatics
Various definitions of Bioinformatics
Evolution of Bioinformatics
Major breakthroughs in Bioinformatics
Bioinformatics and Life Sciences
Bioinformatics and what it means to Life Science
Need of the Biology for Bioinformatics
Bioinformatics and Information Technology
Bioinformatics and what it means to Information Technology
Major study aspects of IT in Bioinformatics
Bioinformatics as a Multidiciplanry Science
Bioinformatics and it’s components
Major study aspects in Bioinformatics
Bioinformatics as a true Integrated Science, Research and Industry.
Bioinformatics Databases,
Need for the Bioinformatics Databases, Tools and Software’s
Data standards in Biology and Bioinformatics
Types of Databases
Sequence Databases
Structural Databases
Functional Databases
Other Important Biological Databases
Module II: Genome Informatics
Introduction to Genomics and Terminology
Central dogma of Molecular Biology
Need for Genomics
Gene Sequence- Structure and Functional relations
Gene Sequence analysis
Introduction to Gene and Genome Sequence analysis
Tools and softwares in Gene and Genome sequence analysis
Comparative Genomics and Phylogenetics
Multiple Gene Sequence analysis
Gene Prediction and Gene Annotations
Gene Identification /Gene Fishing
Gene Annotations
Genome Analysis
Need and Concept of Genome Analysis
Methods used in comparative genomics & Genome Analysis
Genomics as Science & Research
Genes as the major drug targets/ Pharmaco Genomics &Genetics
Gene Annotations and Mapping
Genes and Diseases
Genome Analysis
Module III: Proteome Informatics
Introduction to Proteins
Central dogma of Molecular Biology
Proteins as a major functional units of the living system
Protein structure and it’s complexity
Primary, Secondary, tertiary and quaternary structures
Protein folding and other structural aspects
Protein Databases
Protein Data standards and database design aspects
Types of Databases and database accessibility
Primary, Secondary and Tertiary databases
Protein data retrieval systems and data mining systems
Protein Sequence analysis
Introduction to Protein Sequence analysis
Protein Multiple séquence analysis /Protein Phylogeny
Protein Structure Prediction
Introduction to Insilico Protein structure prediction
Methods in Protein structure prediction
Homology Modelling
Ab-intio methods
2D gel electrophoreses analysis
Protein structure visualization tools and soft wares
Protein Structural Analysis
Various aspects in Protein structural analysis
Protein active site analysis
Protein families, domain and classes
Protein fold recognition methods
Peptide conformation
Proteomics as a Research and Science
Proteins as the major drug targets
Protein folding patterns
Module IV: Cheminformatics
Basics of Chemi-informatics
Introduction to Chemi-informatics
Traditional Drug Discovery
Classification of drugs
Drug discovery
Lead Identification and Isolation
Drug solubility and Drug metabolism
Computer aided drug discovery (CADD)
Basics of CADD Rational Drug designing
Structure based, Ligand based and target oriented drug designing
High throughput screening of chemical libraries
Molecular Modelling/Computational Chemistry
Lead Identification and Validation
Building molecules, conformation searches
Energy minimization
Molecular Dynamics
Quantum mechanics
Drug Targeting and Receptor-Drug Interaction
Basic of Drug targeting
Drug targets and Drug specificity
Pharmaco Dynamics
Pharmaco Kinetics
Pharmaco Genomics Molecular
Docking Methodologies
Drug Validation
Chemical and Physicochemical parameters in Drug designing
Evaluation of ADME properties
QSAR analysis
Recent trends and Future prospects in Chemoinformatics
Personalised/ Individual Drugs
Drug Targeting
